Cavalier King Charles spaniels carry a high number of harmful genes

A genetic study of eight dog breeds including German shepherds and golden retrievers found that cavalier King Charles spaniels had the highest number of potentially harmful mutations

Cavalier King Charles spaniels carry a high number of harmful genes
Life 2 September 2021

By Krista Charles

Two spaniels

Cavalier King Charles spaniels

Ann Tyurina/Shutterstock

Dog breeding has produced canines successful a assortment of shapes and sizes, but has besides led to a build-up of harmful mutations successful definite breeds. A caller survey suggests that cavalier King Charles spaniels transportation a peculiarly precocious level of mutations, including variants linked to a bosom information called myxomatous mitral valve disease.

Erik Axelsson astatine Uppsala University successful Sweden and his colleagues compared the sequenced genomes of 20 idiosyncratic dogs from 8 fashionable canine breeds, specified arsenic German shepherds and aureate retrievers, and recovered that …

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